PhD or Postdoc position at the Asher Lab | Circadian clock resetting and chrono-medicine

The Position | Our lab has a longstanding interest in circadian clock resetting. In previous studies, we have identified and characterized novel resetting cues such as O2 (Adamovich et al., Cell Metabolism 2017) and CO2 (Adamovich et al., Cell Metabolism 2019). Recently, we have developed a new method to study resetting agents in vitro in an efficient and high-throughput manner, dubbed Circa-SCOPE (Manella et al., Nature Communication 2021). This methodology opens the door to wide range of applications, in both basic and translational research. For example, it allows screening multiple drugs (in-use or newly developed) in parallel in order to identify which affects the clock and how – with high relevance to chrono-medicine. It also allows the experimental testing of different models of clock resetting in a quantitative manner. If you decide to join us, you will lead an exciting project combining both wet and computational biology.

What expertise you need? | Experience in programming, preferably in MATLAB, is required. Knowledge and interest in systems biology and mathematical models is advantageous. The project involves tissue culture wet work, but previous experience is not essential.

Why choose us? | The Asher lab is among the leading labs in the field of circadian clocks and metabolism in animals as well as cell culture, using molecular, genetic and bioinformatic approaches. We work in a friendly and collaborative spirit. We are equipped with relevant tools to ensure rapid progress of the projects. The Weizmann Institute is one of the top research institutes in the world. High-end research facilities and services are available on campus. The Weizmann Institute attracts many students and postdocs from around the globe, and has a very strong international community as a result. It is located minutes away from the vibrant life of Tel-Aviv.

Visit our website for more information and publication list.

If you are interested, please contact us by email with your CV and your research interests: Prof Gad Asher (gad.asher@weizmann.ac.il).