Research Assistant III – Cincinnati Children’s Hospital Medical Center

Research Assistant III – Circadian Biology and Obstructive Sleep Apnea
Dr. Koritala Lab at the Cincinnati Children’s Hospital Medical Center

 Are you passionate about unraveling the mysteries of circadian rhythms and their impact on cardiovascular health, particularly in relation to Obstructive Sleep Apnea? Dr. Koritala’s lab is looking for a skilled and enthusiastic Research Assistant III to join their dynamic team.

About Dr. Koritala’s Laboratory:  Dr. Koritala’s lab at the Division of Pediatric Otolaryngology is fully dedicated to understanding the intricate role of circadian clock mechanisms in comorbid cardiovascular disease associated with Obstructive Sleep Apnea (OSA). Our pioneering research revolves around the use of a mouse model of OSA, allowing us to uncover groundbreaking insights into this complex interplay.

Job Description:  As a Research Assistant III, you will play a pivotal role in driving forward our knowledge of circadian rhythms and their profound impact on cardiovascular health associated with OSA. You will be responsible for assisting in the design and execution of experiments, contributing to data collection and analysis, and collaborating with our team of experts to draw meaningful conclusions from our research findings.

• Perform experiments and record data – Follow established research protocols. Understand the scientific principles involved in the research. Apply those principles to troubleshoot and modify procedures and techniques when appropriate. Maintain accurate and detailed records of all laboratory work and experiments. Analyze data and perform statistical and graphical analysis of data. Design and execute daily laboratory experiments in coordination with senior laboratory personnel. Apply standard protocols to specific experiments. Assists in training post-doctoral fellows, graduate students, and junior laboratory personnel in laboratory techniques and equipment. Capable of directing an undergraduate trainee in simple, well-established procedures. Maintains an active role in laboratory’s meetings, presentations, and publications. Contributes material for reports, publications, journal articles, and abstracts. Able to orally present data in group presentations.
• Research and improve current methods – Utilize internal and external resources to reproduce, evaluate, research, and improve techniques, bring in new techniques or modify existing techniques. Evaluate innovative techniques.
• Serve as a Resource – Demonstrate competence in specific knowledge, skills and behaviors. Effectively communicate with team members and contribute to their growth by sharing knowledge, experience, and skills. Stay abreast of changes in key systems. Serve as a resource to the department in specific area(s).
• Lab Administration – Troubleshoot and correct erroneous results or problems with laboratory equipment. Troubleshoot and/or make modifications as necessary to established procedures. Maintain inventory of laboratory supplies and equipment. Maintain cell cultures. Operate standard laboratory equipment. Willing and able to assist in daily operations of the laboratory including answering phone, maintaining lab supplies, organization, and cleanliness. Maintains optimal protocol and assay accuracy by conducting regular quality checks. Provides appropriate safety monitoring checks as assigned (radiation safety, biosafety, etc.)

Required Education/Experience:

• A Bachelor’s or Master’s degree in a relevant field such as Biology, Physiology, Biomedical Sciences, or related disciplines.
• Proven experience in conducting laboratory experiments and working with animal models, preferably mice.
• Strong expertise in Basic Biochemistry and Molecular Biology Techniques, from DNA and RNA extraction to PCR and Immunoblotting. (DNA and RNA extraction, qRT-PCR, Immunoblotting, Immunofluorescence, etc)
• Strong organizational skills, attention to detail, and the ability to multitask effectively.
• Excellent communication and interpersonal skills, with the ability to work collaboratively in a team-oriented environment.
• As this is a circadian lab, the working hours may vary, particularly during experiments, necessitating flexibility including the weekends (further details will be provided during interview)

Preferred:

While not required, having a solid understanding of circadian rhythms, cardiovascular physiology, and sleep-related disorders would be an advantage. Additionally, proficiency in data analysis using software such as R, Python or similar tools.

Dr. Koritala’s laboratory provides an invigorating and encouraging work environment, dedicated to nurturing both personal and professional growth. Here, you’ll find ample opportunities to recognize your efforts, as the lab values and acknowledges contributions by offering authorships in publications.

Please send you CV, cover letter detailing your research experience and interests to Dr. Koritala (Bala.koritala@cchmc.org). We look forward to welcoming a talented Research Assistant III to our team!